Dr
Michael Gray
Senior Researcher in Clinical Therapeutic Ultrasound
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Research
All publications by Dr Gray
Cavitation-mediated transcutaneous delivery of protein and nucleotide-based antigen for rapid high-level immune responses
Hettinga JK,  Lyons B,  Balkaran J,  Rijal P,  Dunn‐Lawless D,  Caproni L,  Gray M,  Suslick KS,  Coussios CC,  Carlisle RC,  et al. (2023)
Clinical trial protocol for PanDox: a phase I study of targeted chemotherapy delivery to non-resectable primary pancreatic tumours using thermosensitive liposomal doxorubicin (ThermoDox®) and focused ultrasound
Spiers L,  Gray M,  Lyon P,  Sivakumar S,  Bekkali N,  Scott S,  Collins L,  Carlisle R,  Wu F,  Middleton M,  Coussios C-C,  et al. (2023)
Sonosensitive cavitation nuclei-a customisable platform technology for enhanced therapeutic delivery
Lyons B,  Balkaran JPR,  Dunn-Lawless D,  Lucian V,  Keller SB,  O'Reilly CS,  Hu L,  Rubasingham J,  Nair M,  Carlisle R,  Stride E,  Gray M,  Coussios C,  et al. (2023)
Cavitation noise characterization and classification using machine-learning techniques
Usadi LN,  Raymond JL,  Wong C,  Wu Q,  Gray M,  Stride EP,  Roy RA,  Kwan J,  et al. (2023)
Investigation of the ultrasound-mediated toxicity mechanisms of various sonosensitive drugs
Singh K,  Vasilyeva A,  Hu L,  Ruan J-L,  Gray M,  Stride EP,  et al. (2023)
Estimation of Acoustic Power Output from Electrical Impedance Measurements
Csány G,  Gray MD,  Gyöngy M,  et al. (2022)
Bactericidal and anti-biofilm effects of uncharged and cationic ultrasound-responsive nitric oxide microbubbles on Pseudomonas aeruginosa biofilms
LuTheryn G,  Hind C,  Campbell C,  Crowther A,  Wu Q,  Keller SB,  Glynne-Jones P,  Sutton JM,  Webb JS,  Gray M,  Wilks SA,  Stride E,  Carugo D,  et al. (2022)
Correlating high-speed optical imaging and passive acoustic mapping of cavitation dynamics
Wu Q,  Gray M,  Smith C,  Bau L,  Coussios C,  Stride EP,  et al. (2022)
Spatio-temporal evaluation of anti-biofilm cavitation activity by passive acoustic mapping
Keller S,  LuTheryn G,  Gray M,  Stride EP,  Cleveland RO,  Coussios C,  et al. (2022)
Large-volume hyperthermia for safe and cost-effective targeted drug delivery using a clinical ultrasound-guided focused ultrasound device
Lyon PC,  Mannaris C,  Gray M,  Carlisle R,  Gleeson FV,  Cranston D,  Wu F,  Coussios CC,  et al. (2021)
Ultrasound mediated gemcitabine delivery reduces the normal tissue toxicity of chemoradiation therapy in a muscle-invasive bladder cancer model
Ruan J-L,  Browning R,  Yildiz Y,  Gray M,  Bau L,  Sukanta K,  Thompson J,  Elliott A,  Smart S,  McHale A,  Callan J,  Vojnovic B,  Stride E,  Kiltie A,  et al. (2021)
Evaluation of loading strategies to improve tumor uptake of gemcitabine in a murine orthotopic bladder cancer model using ultrasound and microbubbles
Ruan J-L,  Browning R,  Yildiz Y,  Bau L,  Gray M,  Folkes L,  Hampson A,  McHale A,  Callan J,  Vojnovic B,  Kiltie A,  Stride E,  et al. (2021)
Studying cavitation enhanced therapy
Gray M,  Vasilyeva AV,  Brans V,  Stride E,  et al. (2021)
Gas-stabilizing solid cavitation nuclei for systemic or transdermal ultrasound-enhanced drug and vaccine delivery and immunomodulation
Lyons B,  Hettinga J,  Balkaran J,  Collins A,  Maardalen M,  Katti P,  Mannaris C,  Bau L,  Smith C,  Gray M,  Kwan J,  Carlisle R,  Coussios C,  et al. (2021)
Dual array passive acoustic mapping for cavitation imaging with enhanced 2-D resolution
Gray M,  Elbes D,  Paverd C,  Lyka E,  Coviello C,  Cleveland RO,  Coussios C-C,  et al. (2020)
Microbubbles containing lysolipid enhance ultrasound‐mediated blood–brain barrier breakdown in vivo
Vince O,  Peeters S,  Johanssen VA,  Gray M,  Smart S,  Sibson NR,  Stride E,  et al. (2020)
Weight for it… adaptive beamformers in passive acoustic mapping for cavitation imaging
Gray M,  Coviello C,  Gyongy M,  Lyka E,  Paverd C,  Crake C,  Elbes D,  Smith C,  Coussios C,  et al. (2020)
Focused ultrasound hyperthermia for targeted drug release from thermosensitive liposomes: results from a phase I trial
Gray MD,  Lyon P,  Mannaris C,  Folkes L,  Stratford M,  Campo L,  Chung DYF,  Scott S,  Anderson M,  Goldin R,  Carlisle R,  Wu F,  Middleton M,  Gleeson F,  Coussios C,  et al. (2019)
Focused Ultrasound Hyperthermia for Targeted Drug Release from Thermosensitive Liposomes: Results from a Phase I Trial.
Lyon PC,  Mannaris C,  Folkes LK,  Stratford M,  Campo L,  Chung DYF,  Scott S,  Anderson M,  Goldin R,  Carlisle R,  Wu F,  Middleton MARK,  Gleeson FV,  Coussios CC,  et al. (2019)
Microbubbles, nanodroplets and gas-stabilizing solid particles for ultrasound-mediated extravasation of unencapsulated drugs: an exposure parameter optimization study.
Mannaris C,  Bau L,  Grundy M,  Gray M,  Lea-Banks H,  Seth A,  Teo B,  Carlisle R,  Stride E,  Coussios C,  et al. (2019)
Ultrasound-mediated cavitation enhances the delivery of an EGFR-targeting liposomal formulation designed for chemo-radionuclide therapy
Thomas E,  Menon JU,  Owen J,  Skaripa-Koukelli I,  Wallington S,  Gray M,  Mannaris C,  Kersemans V,  Allen D,  Kinchesh P,  Smart S,  Carlisle R,  Vallis K,  et al. (2019)
Investigating the role of lipid transfer in microbubble-mediated drug delivery
Aron M,  Vince O,  Gray M,  Mannaris C,  Stride E,  et al. (2019)
Magnetic microbubble mediated chemo-sonodynamic therapy using a combined magnetic-acoustic device
Beguin E,  Logan KA,  Nesbitt H,  Sheng Y,  Kamila S,  Barnsley LC,  Bau L,  McHale AP,  Callan JF,  Stride E,  et al. (2019)
Ultrasound-Induced Mircobubble Cavitation For Optimisation Of Tumour Uptake Of Liposome-Based Chemo-Radionuclide Therapy
Vallis KA,  Thomas E,  Menon J,  Owen J,  Wallington S,  Gray M,  Skaripa-Koukelli I,  Carlisle R,  et al. (2019)
Indium-111 labelling of liposomal HEGF for radionuclide delivery via ultrasound-induced cavitation
Owen J,  Thomas E,  Menon J,  Gray M,  Skaripa-Koukelli I,  Gill ,  Wallington S,  Miller RL,  Vallis K,  Carlisle R,  et al. (2019)
Horses for courses (or something much smaller!): The design, development and acoustic testing of sub-micron cavitation nucleation agents for biomedical applications
Mannaris C,  Bau L,  Kwan JJ,  Teo B,  Gray M,  Elbes D,  Smith C,  Paverd C,  Carlisle R,  Stride EP,  Coussios C,  et al. (2019)
A combined magnetic-acoustic device for simultaneous, co-aligned application of magnetic and ultrasonic fields
Barnsley LC,  Gray MD,  Beguin E,  Carugo D,  Stride EPJ,  et al. (2018)
Passive acoustic mapping using data-adaptive beamforming based on higher-order statistics
Lyka E,  Coviello CM,  Paverd C,  Gray M,  Coussios C,  et al. (2018)
Safety and feasibility of ultrasound-triggered targeted drug delivery of doxorubicin from thermosensitive liposomes in liver tumours (TARDOX): a single-centre, open-label, phase 1 trial
Lyon P,  Gray ,  Mannaris C,  Folkes L,  Stratford M,  Campo L,  Chung DYF,  Scott S,  Anderson M,  Goldin R,  Carlisle R,  Wu F,  Middleton M,  Gleeson F,  Coussios C,  et al. (2018)
Indium-111 afterloading of preformed EGF containing liposomes for molecularly targeted radionuclide delivery via ultrasound induced cavitation
Owen JW,  Menon J,  Gray M,  Thomas E,  Koukelli IS,  Gill M,  Miller R,  Van Blockland A,  Vallis K,  Carlisle R,  et al. (2018)
Antibody targeted ultrasound-responsive nanodroplets for the therapy of brain metastases: A pre-clinical study
Vince O,  Bau L,  Peeters S,  Gray M,  Richards L,  Smart S,  Sibson N,  Stride EP,  et al. (2018)
Investigation of spatio-temporal inertial cavitation activity for optimization of needle-free ultrasound-enhanced vaccine delivery
Dunn-Lawless D,  Balkaran J,  Lyons B,  Carlisle R,  Coussios C,  Gray M,  et al. (2018)
Investigating the role of lipid transfer in sonoporation
Aron M,  Vince O,  Gray M,  Stride EP,  et al. (2018)
Prototypical madness: Design and demonstration of a magnetic-acoustic targeted drug delivery system
Gray M,  Beguin E,  Stride EP,  Nesbitt H,  Logan K,  Kamila S,  McHale A,  Callan J,  Barnsley L,  et al. (2018)
Passive acoustic mapping and B-mode ultrasound imaging utilizing compressed sensing for real-time monitoring of cavitation-enhanced drug delivery
Crake C,  Finn S,  Marsac L,  Gray M,  Carlisle R,  Coussios C,  Coviello C,  et al. (2018)
Diffraction effects and compensation in passive acoustic mapping
Gray MD,  Lyka E,  Coussios C,  et al. (2017)
Bactericidal effect of ultrasound-responsive microbubbles and sub-inhibitory gentamicin against Pseudomonas aeruginosa biofilms on substrates with differing acoustic impedance
Plazonic F,  LuTheryn G,  Hind C,  Clifford M,  Gray M,  Stride E,  Glynne-Jones P,  Hill M,  Sutton JM,  Carugo D,  et al. ()