Professor
Constantin Coussios
MEng MA PhD (Cantab)
Director, Institute of Biomedical Engineering
Professor of Biomedical Engineering
Fellow of Magdalen College
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Research
All publications by Professor Coussios
Passive acoustic mapping of magnetic microbubbles for cavitation enhancement and localization.
Crake C,  Victor MDS,  Owen J,  Coviello C,  Collin J,  Coussios C-C,  Stride E,  et al. (2015)
Inertial cavitation to non-invasively trigger and monitor intratumoral release of drug from intravenously delivered liposomes.
Graham SM,  Carlisle R,  Choi JJ,  Stevenson M,  Shah AR,  Myers RS,  Fisher K,  Peregrino M-B,  Seymour L,  Coussios CC,  et al. (2014)
Properties, characteristics and applications of microbubbles for sonothrombolysis.
de Saint Victor M,  Crake C,  Coussios C-C,  Stride E,  et al. (2014)
Exploitation of acoustic cavitation-induced microstreaming to enhance molecular transport.
Bhatnagar S,  Schiffter H,  Coussios C-C,  et al. (2014)
Exploitation of acoustic cavitation-induced microstreaming to enhance molecular transport
Bhatnagar S,  Schiffter H,  Coussios CC,  et al. (2014)
Normothermic Perfusion of Discarded Human Pancreases.
Ravikumar R,  Coussios C,  Friend P,  et al. (2014)
Non-invasive and real-time passive acoustic mapping of ultrasound-mediated drug delivery.
Choi JJ,  Carlisle RC,  Coviello C,  Seymour L,  Coussios C-C,  et al. (2014)
Normothermic Perfusion of Discarded Human Pancreases
Ravikumar R,  Coussios C,  Friend P,  et al. (2014)
Simulations of ultrasound propagation in a spinal structure.
Qiao S,  Coussios CC,  Cleveland RO,  et al. (2014)
Human Liver Transplantation Using Normothermic Machine Preservation.
Ravikumar R,  Coussios CC,  Holroyd D,  Heaton N,  Friend PJ,  Jassem W,  et al. (2014)
Targeting of liposomes via PSGL1 for enhanced tumor accumulation.
Carlisle R,  Seymour LW,  Coussios CC,  et al. (2013)
A non-exothermic cell-embedding tissue-mimicking material for studies of ultrasound-induced hyperthermia and drug release.
Mylonopoulou E,  Bazán-Peregrino M,  Arvanitis CD,  Coussios CC,  et al. (2013)
Cavitation-enhanced delivery of a replicating oncolytic adenovirus to tumors using focused ultrasound.
Bazan-Peregrino M,  Rifai B,  Carlisle RC,  Choi J,  Arvanitis CD,  Seymour LW,  Coussios CC,  et al. (2013)
Inertial cavitation at the nanoscale.
Kwan JJ,  Graham S,  Coussios C,  et al. (2013)
Passive acoustic mapping of magnetic microbubbles in an in vitro flow model.
Crake C,  de Saint Victor M,  Coviello C,  Owen J,  Coussios CC,  Stride E,  et al. (2013)
Real-time three-dimensional passive cavitation detection for clinical high intensity focused ultrasound systems.
Collin J,  Coviello C,  Lyka E,  Leslie T,  Coussios C,  et al. (2013)
Coating of adenovirus type 5 with cleavable PEGylated gold nanoparticles for enhanced protection and circulation
Mo S,  Carlisle R,  Coussios C-C,  Seymour L,  et al. (2013)
Passive acoustic mapping using optimal beamforming for real-time monitoring of ultrasound therapy
Coviello C,  Kozick RJ,  Choi JJ,  Gyöngy M,  Collin J,  Jensen C,  Smith PP,  Coussios CC,  et al. (2013)
Passive acoustic mapping of magnetic microbubbles in an in vitro flow model
Crake C,  De Saint Victor M,  Coviello C,  Owen J,  Coussios CC,  Stride E,  et al. (2013)
Real-time three-dimensional passive cavitation detection for clinical high intensity focussed ultrasound systems
Collin J,  Coviello C,  Lyka E,  Leslie T,  Coussios CC,  et al. (2013)
Inertial cavitation at the nanoscale
Kwan JJ,  Graham S,  Coussios CC,  et al. (2013)
Calibration of ultrasound backscatter temperature imaging for high-intensity focused ultrasound treatment planning.
Civale J,  Rivens I,  Ter Haar G,  Morris H,  Coussios C,  Friend P,  Bamber J,  et al. (2013)
Calibration of ultrasound backscatter temperature imaging for high-intensity focused ultrasound treatment planning
Civale J,  Rivens I,  ter Haar G,  Morris H,  Coussios C,  Friend P,  Bamber J,  et al. (2013)
Blocking porcine sialoadhesin improves extracorporeal porcine liver xenoperfusion with human blood
Waldman JP,  Vogel T,  Burlak C,  Coussios C,  Dominguez J,  Friend P,  Rees MA,  et al. (2013)
Mechanical approaches to oncological drug delivery.
Carlisle R,  Coussios C-C,  et al. (2013)
Enhanced tumor uptake and penetration of virotherapy using polymer stealthing and focused ultrasound.
Carlisle R,  Choi J,  Bazan-Peregrino M,  Laga R,  Subr V,  Kostka L,  Ulbrich K,  Coussios C,  Seymour LW,  et al. (2013)
Use of micro- and nano-sized inertial cavitation nuclei to trigger and map drug release from cavitation-sensitive liposomes.
Graham SM,  Myers RS,  Choi J,  Bazan-Peregrino M,  Seymour L,  Carlisle R,  Coussios CC,  et al. (2013)
Goldnanoparticles for the enhancement ofadenovirus stealthing
Mo S,  Myers R,  Carlisle R,  Coussios C,  Seymour L,  et al. (2013)
Increased Adenovirus density for increased ultrasound-mediated delivery to tumors
Carlisle RC,  Mo S,  Myers R,  Graham S,  Mylonopoulou E,  Cawood R,  Seymour LW,  Coussios CC,  et al. (2013)
NORMOTHERMIC PERFUSION OF DISCARDED HUMAN PANCREASES
Friend PJ,  Coussios C,  Ravikumar R,  et al. (2013)
Ultrasound-induced cavitation enhances the delivery and therapeutic efficacy of an oncolytic virus in an in vitro model.
Bazan-Peregrino M,  Arvanitis CD,  Rifai B,  Seymour LW,  Coussios C-C,  et al. (2012)
Spatiotemporal monitoring of high-intensity focused ultrasound therapy with passive acoustic mapping.
Jensen CR,  Ritchie RW,  Gyöngy M,  Collin JRT,  Leslie T,  Coussios C-C,  et al. (2012)
Ultrasound-induced cavitation enhances the delivery and therapeutic efficacy of an oncolytic virus in an in vitro model
Bazan-Peregrino M,  Arvanitis CD,  Rifai B,  Seymour LW,  Coussios CC,  et al. (2012)
The role of normothermic extracorporeal perfusion in minimizing ischemia reperfusion injury.
Vogel T,  Brockmann JG,  Coussios C,  Friend PJ,  et al. (2012)
Spatiotemporal quantification of therapeutically relevant cavitation for ablation and drug delivery by ultrasound.
Coussios CC,  Jensen C,  Ritchie R,  Gyongy M,  Hockham N,  Rifai B,  Mylonopoulou E,  Choi J,  Collin JR,  et al. (2012)
Acoustic particle manipulation in a 40 kHz quarter-wavelength standing wave with an air boundary.
Trippa G,  Trine S,  Ventikos Y,  Coussios C-C,  et al. (2012)
Ultrasound-enhanced drug delivery for cancer.
Mo S,  Coussios C-C,  Seymour L,  Carlisle R,  et al. (2012)
Thin-film sparse boundary array design for passive acoustic mapping during ultrasound therapy.
Coviello CM,  Kozick RJ,  Hurrell A,  Smith PP,  Coussios C-C,  et al. (2012)
Targeting of liposomes via PSGL1 for enhanced tumor accumulation
Carlisle R,  Seymour LW,  Coussios CC,  et al. (2012)
Determination of Cytotoxic Thermal Dose During HIFU Ablation
Nandlall SD,  Bazan-Peregrino M,  Mo S,  Coussios C-C,  et al. (2012)
Sonosensitive Nanoparticles for Controlled Instigation of Cavitation and Drug Delivery by Ultrasound
Wagstaffe SJ,  Schiffter HA,  Arora M,  Coussios C-C,  et al. (2012)
Significant Skin Burns May Occur With The Use Of A Water Balloon In HIFU Treatment
Ritchie R,  Collin J,  Wu F,  Coussios C,  Leslie T,  Cranston D,  et al. (2012)
CFD modeling of an ultrasonic separator for the removal of lipid particles from pericardial suction blood.
Trippa G,  Ventikos Y,  Taggart DP,  Coussios C-C,  et al. (2011)
HIFU-induced cavitation and heating in ex vivo porcine subcutaneous fat.
Kyriakou Z,  Corral-Baques MI,  Amat A,  Coussios C-C,  et al. (2011)
Real-time passive acoustic monitoring of HIFU-induced tissue damage.
Nandlall SD,  Jackson E,  Coussios C-C,  et al. (2011)
Blocking porcine sialoadhesin improves extracorporeal porcine liver xenoperfusion with human blood.
Waldman JP,  Vogel T,  Burlak C,  Coussios C,  Dominguez J,  Friend P,  Rees MA,  et al. (2011)
Hepatic steatosis and normothermic perfusion-preliminary experiments in a porcine model.
Jamieson RW,  Zilvetti M,  Roy D,  Hughes D,  Morovat A,  Coussios CC,  Friend PJ,  et al. (2011)
Hepatic steatosis and normothermic perfusion-preliminary experiments in a porcine model
Jamieson RW,  Zilvetti M,  Roy D,  Hughes D,  Morovat A,  Coussios CC,  Friend PJ,  et al. (2011)
Cavitation-Enhanced Extravasation for Drug Delivery
Arvanitis CD,  Bazan-Peregrino M,  Rifai B,  Seymour LW,  Coussios CC,  et al. (2011)
Cavitation-enhanced extravasation for drug delivery.
Arvanitis CD,  Bazan-Peregrino M,  Rifai B,  Seymour LW,  Coussios CC,  et al. (2011)
Effect of temperature on rectified diffusion during ultrasound-induced heating.
Webb IR,  Payne SJ,  Coussios C-C,  et al. (2011)
Ultrasound-enhanced delivery of polymer-coated oncolytic adenovirus for tumour growth inhibition
Carlisle R,  Choi J,  Kostka L,  Bazan-Peregrino M,  Ulbrich K,  Coussios C,  Seymour L,  et al. (2011)
Sonosensitive nanoparticle formulations for cavitation-mediated ultrasonic enhancement of local drug delivery
Wagstaffe SJ,  Arora M,  Coussios CC,  Schiffter HA,  et al. (2011)
An acoustic microscopy technique to assess particle size and distribution following needle-free injection.
Condliffe J,  Schiffter HA,  Cleveland RO,  Coussios C-C,  et al. (2010)
Real-time optical measurement of biologically relevant thermal damage in tissue-mimicking hydrogels containing bovine serum albumin.
Nandlall SD,  Schiffter HA,  Vonhoff S,  Bazán-Peregrino M,  Arora M,  Coussios C-C,  et al. (2010)
Ultrasonic Activation of Thermally Sensitive Liposomes
Mylonopoulou E,  Arvanitis CD,  Bazan-Peregrino M,  Arora M,  Coussios CC,  et al. (2010)
Passive mapping for real-time monitoring of ultrasound therapy.
Coussios CC,  Gyongy M,  Ritchie R,  Webb I,  Nandlall S,  Jackson E,  Arvanitis C,  Bazan-Peregrino M,  Arora M,  et al. (2010)
Exploitation of cavitation-enhanced heating for release of doxorubicin from thermosensitve liposomes by therapeutic ultrasound.
Mylonopoulou E,  Bazan-Peregrino M,  Arvanitis CD,  Coussios CC,  et al. (2010)
Biocompatible solid particles for controlled instigation of cavitation during therapeutic ultrasound.
Arora M,  Schiffter H,  Manhas V,  Wagstaffe S,  Coussios C,  et al. (2010)
Cavitation-enhanced delivery of macromolecules into an obstructed vessel.
Rifai B,  Arvanitis CD,  Bazan-Peregrino M,  Coussios C-C,  et al. (2010)
Dynamics of gas bubbles in time-variant temperature fields
Webb IR,  Arora M,  Roy R,  Payne S,  Coussios C,  et al. (2010)
Robust Capon Beamforming for Passive Cavitation Mapping during HIFU Therapy
Coviello CM,  Faragher S,  Coussios CC,  et al. (2010)
Localization and Interpretation of Bubble Activity during HIFU Exposure
Kennedy P,  Arora M,  Coussios C-C,  et al. (2009)
Normothermic perfusion: a new paradigm for organ preservation.
Brockmann J,  Reddy S,  Coussios C,  Pigott D,  Guirriero D,  Hughes D,  Morovat A,  Roy D,  Winter L,  Friend PJ,  et al. (2009)
Ultrasound-enhanced tissue plasminogen activator thrombolysis in an in vitro porcine clot model.
Holland CK,  Vaidya SS,  Datta S,  Coussios C-C,  Shaw GJ,  et al. (2008)
Ultrasound-enhanced thrombolysis using Definity as a cavitation nucleation agent.
Datta S,  Coussios C-C,  Ammi AY,  Mast TD,  de Courten-Myers GM,  Holland CK,  et al. (2008)
Characterization of ultrasound propagation through ex-vivo human temporal bone.
Ammi AY,  Mast TD,  Huang I-H,  Abruzzo TA,  Coussios C-C,  Shaw GJ,  Holland CK,  et al. (2008)
Use of Passive Arrays for Characterization and Mapping of Cavitation Activity during HIFU Exposure
Gyoengy M,  Arora M,  Noble JA,  Coussios CC,  et al. (2008)
High intensity focused ultrasound: past, present and future.
Haar GT,  Coussios C,  et al. (2007)
Correlation of cavitation with ultrasound enhancement of thrombolysis.
Datta S,  Coussios C-C,  McAdory LE,  Tan J,  Porter T,  De Courten-Myers G,  Holland CK,  et al. (2006)
Use of controlled acoustic cavitation to enhance and monitor cancer treatment by highintensity focussed ultrasound (HIFU)
Coussios C,  Collin J,  Smith M,  et al. (2006)
Development of an acoustic microscopy technique to assess particle distribution following needle-free injection
Condliffe J,  Collin J,  Carter F,  Costigan G,  Coussios CC,  et al. (2006)
Dynamics and control of cavitation during high-intensity focused ultrasound application
Thomas CR,  Farny CH,  Coussios C,  Roy R,  Holt RG,  et al. (2005)
In vitro characterization of liposomes and Optison by acoustic scattering at 3.5 MHz.
Coussios C-C,  Holland CK,  Jakubowska L,  Huang S-L,  MacDonald RC,  Nagaraj A,  McPherson DD,  et al. (2004)